Protein assembly mediated by sulfonatocalix[4]arene.

نویسندگان

  • Róise E McGovern
  • Andrew A McCarthy
  • Peter B Crowley
چکیده

A crystal structure of lysozyme in complex with p-sulfonato-calix[4]arene (sclx4) reveals a linear assembly of protein tetramers glued together by protein-calixarene interactions. One interaction involves encapsulation of the highly exposed C-terminal Arg128. The other involves an intricate protein-bound complex of sclx4, Mg(2+) and a fragment of polyethylene glycol.

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عنوان ژورنال:
  • Chemical communications

دوره 50 72  شماره 

صفحات  -

تاریخ انتشار 2014